Relationships Between the Nicotine Metabolite Ratio (NMR) and Laboratory Assessments of Smoking Reinforcement and Craving Among Adults in a Smoking Cessation Trial.
Robert K CooperMartin C MahoneyStephen T TiffanyCraig R ColderRachel Fynvola TyndaleLarry W HawkPublished in: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco (2023)
Though greater smoking reinforcement, general craving, and cue-specific craving are hypothesized to be linked to faster nicotine metabolism, there was no evidence of such relationships in the present sample of adults seeking to quit smoking. Further research, including replication and consideration of alternate hypotheses, is warranted to elucidate the mechanisms by which the NMR is related to smoking cessation.