Potential Mechanisms Involved in Chronic Kidney Disease of Unclear Etiology.
Michael W HollidayQingtian LiEdlyn G BustamanteJingbo NiuLuping HuangIlse M EspinaJose R DominguezLuan TruongKristy O MurrayLei FanSamaya J AnumuduMaulin ShahRebecca S B FischerChandan VangalaSreedhar MandayamJose PerezJenny S PanSehrish AliAhmed A AwanDavid Sheikh-HamadPublished in: Clinical journal of the American Society of Nephrology : CJASN (2022)
Exposure to agrochemicals is associated with Mesoamerican nephropathy, and chronic exposure of mice to paraquat, a prototypical oxidant, induced kidney failure similar to Mesoamerican nephropathy.