The PYK2 inhibitor PF-562271 enhances the effect of temozolomide on tumor growth in a C57Bl/6-Gl261 mouse glioma model.
Jescelica Ortiz-RiveraRebeca NuñezYuriy V KucheryavykhLilia Y KucheryavykhPublished in: Journal of neuro-oncology (2023)
TMZ + PF-562271 eliminates TMZ-related Pyk2/FAK activation in GBM and improves the treatment efficacy.