Drug-Drug Interactions and Actual Harm to Hospitalized Patients: A Multicentre Study Examining the Prevalence Pre- and Post-Electronic Medication System Implementation.

Ling Li Jannah BakerRenee QuirkDanielle DeidunMaria MoranAhmed Abo SalemNanda Aryal Bethany Annemarie Van DortWu Yi ZhengAndrew HargreavesPaula DohertySarah Nicole Hilmer Richard Osborne Day Johanna I Westbrook Melissa Therese Baysari

Published in: Drug safety (2024)

Although most patients experienced a pDDI during their hospital stay, less than one-third of pDDIs were clinically relevant. The low prevalence of harm identified raises questions about the value of incorporating DDI decision support into systems given the potential negative impacts of DDI alerts.

Keyphrases

healthcare
end stage renal disease
risk factors
adverse drug
newly diagnosed
chronic kidney disease
primary care
prognostic factors
emergency department
quality improvement