Pharmacokinetics After Single Ascending Dose, Food Effect, and Safety of Sacubitril/Valsartan (LCZ696), an Angiotensin Receptor and Neprilysin Inhibitor, in Healthy Japanese Subjects.
Mizuki AkahoriSurya AyalasomayajulaThomas LangenickelParasar PalWei ZhouGangadhar SunkaraPublished in: European journal of drug metabolism and pharmacokinetics (2018)
Single oral doses of up to 600 mg of LCZ696 were safe and generally well tolerated in healthy Japanese male subjects.