Current evidence for the risk of PR prolongation, QRS widening, QT prolongation, from lopinavir, ritonavir, atazanavir, and saquinavir: A systematic review.

Denio A Ridjab Ignatius IvanFanny BudimanDwi Jani Juliawati

Published in: Medicine (2021)

Limited evidence suggests that lopinavir, ritonavir, atazanavir, and saquinavir could cause PR prolongation, QRS widening, and QT prolongation. Further trials with closer monitoring and assessment of electrocardiography are needed to ascertain usage safety of antivirals in COVID-19 era.

Keyphrases

drug induced
coronavirus disease
sars cov
hiv infected patients
antiretroviral therapy
atrial fibrillation