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Ge-gen decoction alleviates primary dysmenorrhoea symptoms in a rat model.

Yazhen XieHaifeng XuZhijuan Gu
Published in: Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology (2024)
The results of this study suggest that GGD alleviates PD in rats by suppressing the COX-2-mediated release of PGE2 and PGF2α, modulating the ERα/ERK1/2/COX-2 pathway, and increasing β-EP content. These results provide insights into the potential mechanisms of GGD in treating PD and support its further investigation as an alternative therapy for this condition.
Keyphrases
  • signaling pathway
  • cell proliferation
  • mouse model
  • estrogen receptor
  • human health
  • depressive symptoms