Second near-infrared photothermal-amplified immunotherapy using photoactivatable composite nanostimulators.

Haitao SunTianzhu YuXin LiYangyang LeiJianke LiXiuhui WangPeike PengDalong NiXiaolin WangYu Luo

Published in: Journal of nanobiotechnology (2021)

CNS nanoparticle-mediated photothermal-synergized immunotherapy efficiently suppressed the growth of primary and distant tumors in two mouse models and prevented pulmonary metastasis. This study thus provides a novel sight into photo-controllably safe and efficient immunotherapy.

Keyphrases

photodynamic therapy
mouse model
drug delivery
drug release
pulmonary hypertension
blood brain barrier