Off-Label Reduced Dose Apixaban in Older Adults With Atrial Fibrillation and Associated Outcomes.
Ashley M CampbellElizabeth PaeEunice LeeTimothy JacisinAlina PriceJessica DeAngeloPublished in: The Annals of pharmacotherapy (2023)
Older adults with nonvalvular AF are commonly prescribed lower-than-recommended doses of apixaban. However, no significant association was found between empiric off-label reduced dosing and stroke or bleeding outcomes.
Keyphrases
- atrial fibrillation
- oral anticoagulants
- left atrial
- catheter ablation
- left atrial appendage
- direct oral anticoagulants
- heart failure
- physical activity
- community dwelling
- middle aged
- percutaneous coronary intervention
- adipose tissue
- skeletal muscle
- venous thromboembolism
- brain injury
- urinary tract infection
- cerebral ischemia