Acquisition of carbapenem-resistant gram-negative bacilli among intensive care unit (ICU) patients with no previous use of carbapenems: Indirect population impact of antimicrobial use.
Juliana da Silva OliveiraNatalie Carlos Ferreira Melo SampaioGabriela Silveira LeiteMilena Aparecida Del Masso PereiraCarlos Magno Castelo Branco FortalezaPublished in: Infection control and hospital epidemiology (2022)
Every additional DOT of total carbapenem use increased the risk of CR-GNB acquisition by patients not using carbapenems by nearly 1%. We found evidence for a population ("herd effect"-like) impact of antimicrobial use in the ICUs.
Keyphrases
- gram negative
- intensive care unit
- multidrug resistant
- staphylococcus aureus
- end stage renal disease
- ejection fraction
- mechanical ventilation
- newly diagnosed
- acinetobacter baumannii
- drug resistant
- prognostic factors
- klebsiella pneumoniae
- peritoneal dialysis
- cystic fibrosis
- quantum dots
- acute respiratory distress syndrome