Login / Signup

Toxic anterior segment syndrome following phakic posterior chamber IOL: a rarity.

Archita SinghPraveen VashistVinod KumarRadhika Tandon
Published in: BMJ case reports (2018)
Implantable collamer lenses (ICL) have gained popularity for correction of myopia where kerato-refractive procedures are not indicated as in cases of high myopic refractive errors. Toxic anterior segment syndrome (TASS) is a very uncommonly reported postoperative complication following ICL implantation. A young patient developed severe corneal oedema and anterior segment inflammation on the first day after ICL implantation. Analysing retrospectively, possible idiosyncratic response to intracameral pilocarpine was considered as a cause for TASS. Prompt and intensive therapy with oral and topical potent steroids was visually rewarding. TASS, though a sterile inflammation can have catastrophic sequelae such as corneal decompensation and secondary glaucoma. Hence, timely identification and management is important.
Keyphrases
  • cataract surgery
  • case report
  • oxidative stress
  • wound healing
  • drug induced
  • early onset
  • optical coherence tomography
  • stem cells
  • mesenchymal stem cells
  • adverse drug
  • electronic health record