Treatment of Cardiac Rhabdomyomas with mTOR Inhibitors in Children with Tuberous Sclerosis Complex-A Systematic Review.

Monika SugalskaAnna TomikSergiusz Jozwiak Bozena Werner

Published in: International journal of environmental research and public health (2021)

mTORi may be considered as a temporary and safe treatment for symptomatic CRs in children with TSC, especially in high-risk or inoperable tumors. However, high-quality, randomized trials are still lacking.

Keyphrases

young adults
squamous cell carcinoma
cell proliferation
heart failure
combination therapy
replacement therapy