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A novel progesterone receptor membrane component (PGRMC) in the human and swine parasite Taenia solium: implications to the host-parasite relationship.

Hugo Aguilar-DíazKaren E Nava-CastroGalileo EscobedoLenin Domínguez-RamírezMartín García-VarelaVíctor H Del Río-AraizaMargarita I Palacios-ArreolaJorge Morales Montor
Published in: Parasites & vectors (2018)
Progesterone may directly act upon T. solium cysticerci probably by binding to PGRMC. This research has implications in the field of host-parasite co-evolution as well as the sex-associated susceptibility to this infection. In a more practical matter, present results may contribute to the molecular design of new drugs with anti-parasite actions.
Keyphrases
  • plasmodium falciparum
  • toxoplasma gondii
  • trypanosoma cruzi
  • life cycle
  • endothelial cells
  • estrogen receptor
  • induced pluripotent stem cells