Hypertonic sodium lactate improves microcirculation, cardiac function, and inflammation in a rat model of sepsis.

Emmanuel BesnierDavid CoquerelGeoffrey KouadriThomas ClavierRaphael FavoryThibault DuburcqOlivier LesurSoumeya BekriVincent RichardPaul MulderFabienne Tamion

Published in: Critical care (London, England) (2020)

Hypertonic sodium lactate fluid protects against cardiac dysfunction, mesenteric microcirculation alteration, and capillary leakage during sepsis and simultaneously reduces inflammation and enhances ketone bodies.

Keyphrases

oxidative stress
septic shock
acute kidney injury
intensive care unit
left ventricular
heart failure