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Malignancies in Prader-Willi syndrome: results from a large international cohort and literature review.

Karlijn PellikaanNaomi Q C NguyenAnna G W RosenbergMuriel CoupayeAnthony Peter GoldstoneCharlotte HøybyeTania MarkovicGraziano GrugniAntonino CrinòAssumpta CaixàsChristine PoitouRaquel CorripioRosa M NieuwenhuizeAart J van der LelyLaura C G de Graaff
Published in: The Journal of clinical endocrinology and metabolism (2023)
Malignancies are rare in patients with PWS. Therefore, screening for malignancies is only indicated when clinically relevant symptoms are present such as unexplained weight loss, loss of appetite, symptoms suggestive of paraneoplastic syndrome, or localizing symptoms. Given the increased cancer risk associated with obesity, which is common in PWS, participation in national screening programs should be encouraged.
Keyphrases
  • weight loss
  • case report
  • bariatric surgery
  • roux en y gastric bypass
  • sleep quality
  • public health
  • type diabetes
  • physical activity
  • weight gain
  • obese patients