Morphological and molecular changes of oestrogen receptor-positive breast cancer following bridging endocrine therapy: a United Kingdom multicentre study.

Islam M MiligyRachna AwasthiYasmeen MirAnuj KhuranaVijay SharmaUsha ChandaranEmad RakhaYasmine MauriceDaniel KearnsRami OweisAmal AsarAlastair IronsideAbeer M Shaaban

Published in: Histopathology (2024)

Changes characteristic of tumour regression and significant changes in PR and HER2 occurred following a short course of NAET. The findings support biomarker testing on pretreatment core biopsies and retesting following therapy.

Keyphrases

positive breast cancer
stem cells
single molecule
bone marrow
smoking cessation