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MBL Binding with AhR Controls Th17 Immunity in Silicosis-Associated Lung Inflammation and Fibrosis.

Yunzhi LiuNa ZhaoQishan XuFan DengPing WangLijun DongXiao LuLihua XiaMingyong WangZhengliang ChenJia ZhouDaming Zuo
Published in: Journal of inflammation research (2022)
Our study suggested that MBL limited the Th17 immunity via controlling the AhR/STAT3 pathway, thus providing new insight into silicosis and other inflammatory diseases in patients with MBL deficiency.
Keyphrases
  • oxidative stress
  • pulmonary fibrosis
  • cell proliferation
  • transcription factor