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Synthesis, characterization and evaluation of transfection efficiency of dexamethasone conjugated poly(propyleneimine) nanocarriers for gene delivery#.

Bizhan Malaekeh-NikoueiMehdi RezaeeLeila GholamiNaghmeh Sanjar MousaviReza Kazemi Oskuee
Published in: Pharmaceutical biology (2019)
The modification of PPIs with Dexa is a promising approach to improve their cytotoxicity and transfection. The higher optimization of physicochemical characteristics, the better cell transfection and toxicity will be achieved.
Keyphrases
  • drug delivery
  • single cell
  • cell therapy
  • low dose
  • photodynamic therapy
  • oxidative stress
  • high dose
  • stem cells
  • cancer therapy
  • drug release
  • mesenchymal stem cells