Mismatch Repair Deficiency Is a Prognostic Factor Predicting Good Survival of Opisthorchis viverrini -Associated Cholangiocarcinoma at Early Cancer Stage.

Natcha KhuntikeoSureerat PadthaisongWatcharin Loilome Poramate KlanritSoontaree RatchatapusitAnchalee TechasenApiwat JareanratVasin ThanasukarnTharatip SrisukVor LuviraJarin ChindaprasertPrakasit Sa-NgiamwiboolChaiwat Aphivatanasiri Piyapharom Intarawichian Supinda KoonmeePiya PrajumwongsAttapol Titapun

Published in: Cancers (2023)

This study showed a high prevalence of dMMR in cholangiocarcinoma with dMMR being the independent prognostic factor for good survival, especially in early-stage CCA and for patients who received adjuvant chemotherapy. dMMR should be the marker for selecting patients to receive a specific adjuvant treatment after resection for CCA.

Keyphrases

prognostic factors
early stage
papillary thyroid
squamous cell carcinoma
replacement therapy
combination therapy
neoadjuvant chemotherapy
locally advanced