Low-profile patterned plasmonic surfaces are synergized with a broad class of silicon microstructures to greatly enhance near-field nanoscale imaging, sensing, and energy harvesting coupled with far-field free-space detection. This concept has a clear impact on several key areas of interest for the MEMS community, including but not limited to ultra-compact microsystems for sensitive detection of small number of target molecules, and "surface" devices for optical data storage, micro-imaging and displaying. In this paper, we review the current state-of-the-art in plasmonic theory as well as derive design guidance for plasmonic integration with microsystems, fabrication techniques, and selected applications in biosensing, including refractive-index based label-free biosensing, plasmonic integrated lab-on-chip systems, plasmonic near-field scanning optical microscopy and plasmonics on-chip systems for cellular imaging. This paradigm enables low-profile conformal surfaces on microdevices, rather than bulk material or coatings, which provide clear advantages for physical, chemical and biological-related sensing, imaging, and light harvesting, in addition to easier realization, enhanced flexibility, and tunability.
Keyphrases
- label free
- high resolution
- single molecule
- sensitive detection
- energy transfer
- mental health
- biofilm formation
- high throughput
- healthcare
- physical activity
- quantum dots
- escherichia coli
- circulating tumor cells
- fluorescence imaging
- big data
- staphylococcus aureus
- deep learning
- photodynamic therapy
- pseudomonas aeruginosa
- cystic fibrosis
- data analysis
- electron microscopy