Differential expression and methylation of integrin subunit alpha 11 and thrombospondin in the amnion of preterm birth.

Jae Young YooYoung-Ah YouEun Jin KwonMi Hye ParkSunah ShimYoung Ju Kim

Published in: Obstetrics & gynecology science (2018)

Methylation of the ITGA11 and THBS2 genes in the amnion was associated with preterm birth. Thus, ITGA11 and THBS2 gene methylation status in the amnion may be valuable in explaining the mechanism underlying preterm birth.

Keyphrases

preterm birth
genome wide
dna methylation
low birth weight
gestational age
copy number
gene expression
genome wide analysis