Transcriptome Analysis of Hypertrophic Heart Tissues from Murine Transverse Aortic Constriction and Human Aortic Stenosis Reveals Key Genes and Transcription Factors Involved in Cardiac Remodeling Induced by Mechanical Stress.
Peng YuBaoli ZhangMing LiuYing YuJi ZhaoChunyu ZhangYana LiLei ZhangXue YangHong JiangYunzeng ZouJun-Bo GePublished in: Disease markers (2019)
This study unravels the complex transcriptome profiles of the heart tissues and highlighting the candidate genes involved in cardiac remodeling induced by mechanical stress may usher in a new era of precision diagnostics and treatment in patients with cardiac remodeling.
Keyphrases
- left ventricular
- aortic stenosis
- aortic valve
- gene expression
- heart failure
- transcatheter aortic valve replacement
- aortic valve replacement
- ejection fraction
- transcatheter aortic valve implantation
- transcription factor
- genome wide
- atrial fibrillation
- neuropathic pain
- stress induced
- pulmonary artery
- dna methylation
- spinal cord
- induced pluripotent stem cells
- pulmonary arterial hypertension
- pulmonary hypertension