Novel insights into a reputably irreversible process: combined mRNA and miRNA profiling of tissue from vesicourethral anastomotic stenosis after radical prostatectomy.

T S WorstK DaskalovaA SteidlerK Berner-LeischnerR RöthB NieslerC-A WeisM C KriegmairP ErbenDaniel Pfalzgraf

Published in: World journal of urology (2017)

In VUAS tissue, severe alterations on mRNA and miRNA level are found. These consistent changes give insights into the pathogenesis of VUAS after radical prostatectomy and point to future options for transcriptomics-based risk stratification and targeted therapies.

Keyphrases

radical prostatectomy
prostate cancer
single cell
binding protein
early onset
current status
drug induced