Biology of primary breast cancer in older women beyond routine biomarkers.
R M ParksL H AlfarsiA R GreenKwok Leung CheungPublished in: Breast cancer (Tokyo, Japan) (2021)
There is evidence to support further investigation of B-cell lymphoma (BCL2), liver kinase (LK)B1, epidermal growth factor receptor (EGFR), cytoplasmic cyclin-E, mucin (MUC)1 and cytokeratins (CKs) as potential predictive or prognostic markers in older women with breast cancer undergoing surgery. Studies exploring these biomarkers in larger cohorts and in women undergoing non-operative therapies are required.
Keyphrases
- epidermal growth factor receptor
- tyrosine kinase
- advanced non small cell lung cancer
- minimally invasive
- polycystic ovary syndrome
- coronary artery bypass
- cell cycle
- diffuse large b cell lymphoma
- small cell lung cancer
- physical activity
- clinical practice
- breast cancer risk
- middle aged
- community dwelling
- pregnancy outcomes
- pregnant women
- skeletal muscle
- cell death
- metabolic syndrome
- protein kinase
- adipose tissue
- risk assessment
- young adults
- atrial fibrillation
- climate change
- percutaneous coronary intervention
- pi k akt
- childhood cancer