Development and validation of an ELISA for a biomarker of thyroid dysfunction, thyroid peroxidase autoantibodies (TPO-Ab), in dried blood spots.

Geeta N EickTara J Cepon-RobinsMaureen J DevlinPaul KowalLarry S SugiyamaJ Josh Snodgrass

Published in: Journal of physiological anthropology (2020)

We developed an in-house, kit-independent indirect ELISA assay to determine individuals' TPO-Ab positivity based on dried blood spots, representing a cost-effective method with potential applications in a range of research settings.

Keyphrases

systemic lupus erythematosus
oxidative stress
high throughput
monoclonal antibody
hydrogen peroxide
risk assessment
nitric oxide
human health