Key inflammatory pathway activations in the MCI stage of Alzheimer's disease.

Jagan A PillaiSean MaxwellJames BenaLynn M BekrisStephen M RaoMark ChanceBruce T LambJames B Leverenznull null

Published in: Annals of clinical and translational neurology (2019)

A cell-protective rather than a proinflammatory analyte profile predominates in the CSF in relation to neurodegeneration markers among MCI-AD patients. Analytes from the TNF signaling and the complement and coagulation pathways are relevant in evaluating disease severity at the MCI stage of AD.

Keyphrases

mild cognitive impairment
end stage renal disease
ejection fraction
newly diagnosed
cognitive decline
rheumatoid arthritis
peritoneal dialysis
oxidative stress
prognostic factors
cell therapy
bone marrow
patient reported