Association of systemic inflammation and body mass index with survival in patients with resectable gastric or gastroesophageal junction adenocarcinomas.

Xianchun GaoYanan PanWeili HanCaie HuChenchen WangLing ChenYong GuoYupeng ShiYan PanHuahong XieLiping YaoJianjun YangJianyong ZhengXiaohua LiXiaonan LiuLiu HongJipeng LiMengbin LiGang JiZengshan LiJielai XiaQingchuan ZhaoDaiming FanKaichun WuYong-Zhan Nie

Published in: Cancer biology & medicine (2021)

Our results showed that preoperative elevated NLR and decreased BMI had a significant negative effect on survival. Underweight combined with severe inflammation could enhance prognostication. Taking active therapeutic measures to reduce inflammation and increase nutrition may help improve outcomes.

Keyphrases

body mass index
oxidative stress
physical activity
weight gain
free survival
patients undergoing
early onset
squamous cell carcinoma
insulin resistance
glycemic control
drug induced