Challenging the gold standard: methods of sampling for microbial culture in patients with chronic rhinosinusitis.
Joanna SzaleniecAgnieszka GibałaPatryk HartwichKarolina Hydzik-SobocińskaMarcin KoniorTomasz GosiewskiMaciej SzaleniecPublished in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2021)
The traditional method of sampling from the middle meatus provides inadequate information in 24% of patients with CRS, which may result in inadequate antibiotic therapy and contribute to increasing antibiotic resistance. Additional sampling from the sinuses should be recommended whenever possible, while invasive sampling is not necessary.