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Association of facility type with overall survival in patients with nonsurgically managed pancreatic cancer.

Josiah McAllisterSaber A AminChi Lin
Published in: Future oncology (London, England) (2022)
Aim: To investigate the association between receiving treatment at academic centers and overall survival in pancreatic ductal adenocarcinoma patients who do not receive definitive surgery of the pancreatic tumor. Methods: Using the National Cancer Database, patients who were diagnosed with pancreatic ductal adenocarcinoma between 2004 to 2016 were identified. Results: Of 262,209 patients, 101,003 (38.5%) received treatment at academic centers. In the multivariable Cox regression analysis, patients who received treatment at a nonacademic facility had significantly worse overall survival compared with patients who were treated at an academic center (hazard ratio: 1.279; 95% CI: 1.268-1.290; p = 0.001). Conclusion: Compared with treatment at academic centers, treatment at nonacademic centers was associated with significantly worse overall survival in patients with nonsurgically managed pancreatic ductal adenocarcinoma.
Keyphrases
  • newly diagnosed
  • squamous cell carcinoma
  • radiation therapy
  • free survival
  • acute coronary syndrome
  • locally advanced
  • drug induced