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Genome-wide and phenome-wide analysis of ideal cardiovascular health in the VA Million Veteran Program.

Rose D L HuangXuan-Mai T NguyenGina M PelosoMark TrinderDaniel C PosnerKrishna G AragamYuk-Lam HoJulie A LynchScott M DamrauerKyong-Mi ChangPhilip S TsaoPradeep NatarajanThemistocles AssimesJ Michael GazianoLuc DjousseKelly ChoPeter W F WilsonJennifer E HuffmanChristopher J O'Donnellnull null
Published in: PloS one (2022)
A set of high interest genetic variants contribute to the presence of ideal CVH in a multi-ethnic cohort of US Veterans. Genetically influenced ideal CVH is associated with lower odds of CVD outcomes and mortality.
Keyphrases
  • genome wide
  • dna methylation
  • cardiovascular events
  • quality improvement
  • cardiovascular disease
  • gene expression
  • metabolic syndrome
  • adipose tissue
  • skeletal muscle
  • insulin resistance