Volumetric changes and clinical trajectories in Parkinson's disease: a prospective multicentric study.

Ana-Raquel MarquesElise MaciasBruno PereiraElodie DurandCarine ChassainTiphaine VidalLuc DefebvreNicolas CarriereValerie FraixElena MoroStéphane ThoboisElise MetereauGraziella MangoneMarie VidailhetJean-Christophe CorvolStéphane LehéricyNicolas Menjot de ChampfleurChristian GenyUmberto SpampinatoWassilios G MeissnerSolène FrismandEmmanuelle SchmittAnne Doé de MaindrevilleChristophe PortefaixPhilippe RemyGilles FénelonJean Luc HouetoOlivier ColinOlivier RascolPatrice PeranJean-Marie BonnyMaria Livia FantiniFranck Durifnull null

Published in: Journal of neurology (2023)

Brain volumetric characteristics at baseline may predict clinical trajectories at 1 year in PD as posterior cingulate cortex atrophy was associated with motor decline, while amygdala and hippocampus atrophy were associated with psycho-behavioral decline.

Keyphrases

functional connectivity
resting state
depressive symptoms
white matter
cerebral ischemia
prefrontal cortex