Predicting Loss of Efficacy after Non-Medical Switching: Correlation between Circulating TNF-α Levels and SB4 in Etanercept to SB4 Switchers and Naïve Patients with Rheumatic Disease.

Maurizio BenucciArianna DamianiEdda RussoFrancesca Li GobbiValentina GrossiAmedeo AmedeiMaria InfantinoMariangela Manfredi

Published in: Journal of personalized medicine (2022)

We observed a decrease in DL and TNF-α levels after NMS in SNR. Moreover, in naïve patients, DL and TNF-α levels were higher in NR than in NNR. Monitoring DL and TNF-α levels may represent a future precision medicine approach to predict loss of efficacy after NMS.

Keyphrases

rheumatoid arthritis
end stage renal disease
chronic kidney disease
disease activity
ankylosing spondylitis
prognostic factors
juvenile idiopathic arthritis