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Crosstalk between immune checkpoint and DNA damage response inhibitors for radiosensitization of tumors.

Sandra ClassenCordula PetersenKerstin Borgmann
Published in: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] (2023)
The combination of tested inhibitors of DNA damage and immune responses in preclinical models opens additional attractive options for the radiosensitization of tumors and represents a promising application for future therapeutic approaches.
Keyphrases
  • dna damage response
  • dna damage
  • dna repair
  • immune response
  • oxidative stress
  • current status
  • dendritic cells
  • stem cells
  • toll like receptor