Involvement of Muscarinic M3 Receptor in the Development of M2 Macrophages in Allergic Inflammation.
Megumi JinnoShin OhtaHatsuko MikuniTomoki UnoYoshitaka UchidaRyo ManabeYoshito MiyataTetsuya HommaYoshio WatanabeSojiro KusumotoShintaro SuzukiAkihiko TanakaHironori SagaraPublished in: International archives of allergy and immunology (2024)
Muscarinic M3 receptor blockage inhibits M2 macrophage development and prevents allergic airway inflammation. Moreover, muscarinic M3 receptors might be involved in the differentiation of immature macrophages into M2 macrophages.