Lipoprotein(a) is associated with the onset but not the progression of aortic valve calcification.
Yannick KaiserJanine E van der ToornSunny S SinghKang H ZhengMaryam KavousiEric J G SijbrandsErik S G StroesMeike W VernooijYolanda B de RijkeS Matthijs BoekholdtDaniel BosPublished in: European heart journal (2022)
In the population-based Rotterdam Study, Lp(a) is robustly associated with baseline and new-onset AVC but not with AVC progression, suggesting that Lp(a)-lowering interventions may be most effective in pre-calcific stages of aortic valve disease.