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Lipoprotein(a) is associated with the onset but not the progression of aortic valve calcification.

Yannick KaiserJanine E van der ToornSunny S SinghKang H ZhengMaryam KavousiEric J G SijbrandsErik S G StroesMeike W VernooijYolanda B de RijkeS Matthijs BoekholdtDaniel Bos
Published in: European heart journal (2022)
In the population-based Rotterdam Study, Lp(a) is robustly associated with baseline and new-onset AVC but not with AVC progression, suggesting that Lp(a)-lowering interventions may be most effective in pre-calcific stages of aortic valve disease.
Keyphrases
  • aortic valve
  • transcatheter aortic valve replacement
  • transcatheter aortic valve implantation
  • aortic valve replacement
  • aortic stenosis
  • physical activity
  • chronic kidney disease
  • heart failure