The Number and Size of Individual Kidney Medullary Pyramids is Associated with Clinical Characteristics, Kidney Biopsy Findings, and CKD Outcomes among Kidney Donors.
Adriana V GregoryAleksandar DenicAmr MoustafaPraveen G DasarajuBhavya PoudyalJoshua J AugustineAidan F MullanPanagiotis KorffiatisAndrew D RuleTimothy L KlinePublished in: Journal of the American Society of Nephrology : JASN (2023)
Cortical volume and medullary pyramid volume and count reflect underlying variation in nephron number and nephron size, as well as merging of pyramids due to age-related nephrosclerosis, with loss of detectable cortical columns separating pyramids.