The Gut Microbial Metabolite Trimethylamine N-oxide, Incident CKD, and Kidney Function Decline.
Meng WangW H Wilson TangXinmin S LiMarcia C de Oliveira OttoYujin LeeRozenn N LemaitreAmanda M FrettsIna NemetNona SotoodehniaColleen M SitlaniMatthew J BudoffJoseph A DiDonatoZeneng WangNisha BansalMichael G ShlipakBruce M PsatyDavid S SiscovickMark J SarnakDariush MozaffarianStanley L HazenPublished in: Journal of the American Society of Nephrology : JASN (2024)
In community-based US adults, higher serial measures of plasma TMAO were associated with higher risk of incident CKD and greater annualized kidney function decline.