Current jakinibs for the treatment of rheumatoid arthritis: a systematic review.

Cláudia Monfroni RochaAlessandro Menna AlvesBeatriz Fabris BettaninFernanda MajoloMatthias GehringerStefan LauferMárcia Ines Goettert

Published in: Inflammopharmacology (2021)

Jakinibs in monotherapy or in combination with methotrexate can be considered a viable alternative in the treatment of moderate-to-severe RA. Even after failures with combination of cDMARDS and bDMARDS, jakinibs demonstrated efficacy.

Keyphrases

rheumatoid arthritis
combination therapy
disease activity
clinical trial
high dose
systemic lupus erythematosus
interstitial lung disease
high intensity
ankylosing spondylitis
replacement therapy
smoking cessation
double blind