Calcio-Herbal Medicine Divya-Swasari-Vati Ameliorates SARS-CoV-2 Spike Protein-Induced Pathological Features and Inflammation in Humanized Zebrafish Model by Moderating IL-6 and TNF-α Cytokines.

Acharya BalkrishnaSudeep VermaSiva Kumar SolletiLakshmipathi Khandrika Anurag Varshney

Published in: Journal of inflammation research (2020)

The study showed that the A549 xenotransplanted zebrafish injected with the recombinant spike protein of SARS-CoV-2 is an efficient model for the disease; and treatment with Divya-Swasari-Vati medicine rescued most of the inflammatory damage caused by the viral spike protein while increasing survival of the experimental fish.

Keyphrases

sars cov
oxidative stress
protein protein
respiratory syndrome coronavirus
amino acid
rheumatoid arthritis
binding protein
small molecule
mouse model
depressive symptoms
combination therapy
cell free
replacement therapy
stress induced