Reciprocal regulation of forkhead box C1 and L1 cell adhesion molecule contributes to triple-negative breast cancer progression.

Fan ZhangYue XuJiediao LinHongchao PanArmando E GiulianoXiaojiang CuiYukun Cui

Published in: Breast cancer research and treatment (2024)

FOXC1 and L1CAM exhibit co-regulation at the protein level, with FOXC1 regulating at the transcriptional level and L1CAM regulating at the post-transcriptional level, and together they positively influence cell proliferation, migration, and invasion in TNBC.

Keyphrases

transcription factor
cell adhesion
cell proliferation
gene expression
cell cycle
oxidative stress
pi k akt
small molecule