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Hyper-connectivity between the left motor cortex and prefrontal cortex is associated with the severity of dysfunction of the descending pain modulatory system in fibromyalgia.

Álvaro de Oliveira FrancoCamila Fernanda da Silveira AlvesPaul VicuñaJanete Shatkoski BandeiraMaria Adelia de AratanhaIraci L S TorresFelipe FregniWolnei Caumo
Published in: PloS one (2022)
Higher FC between the lMC and the bilateral PFC may be a neural marker of DPMS dysfunction in women with fibromyalgia, although its interplay with psychiatric diagnoses also seems to influence this association.
Keyphrases
  • prefrontal cortex
  • oxidative stress
  • chronic pain
  • mental health
  • pain management
  • resting state
  • functional connectivity
  • white matter
  • postoperative pain