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Single-cell RNA sequencing of Plasmodium vivax sporozoites reveals stage- and species-specific transcriptomic signatures.

Anthony A RubertoCaitlin BourkeAmélie VantauxSteven P MaherAaron JexBenoit WitkowskiGeorges SnounouIvo Mueller
Published in: PLoS neglected tropical diseases (2022)
In defining the transcriptomic signatures of individual P. vivax sporozoites, our work provides new insights into the factors driving their developmental trajectory and lays the groundwork for a more comprehensive P. vivax cell atlas.
Keyphrases
  • single cell
  • rna seq
  • plasmodium falciparum
  • high throughput
  • genome wide
  • genetic diversity
  • mesenchymal stem cells