Login / Signup

Apiosporamide, A 4-hydroxy-2-pyridone Alkaloid, Induces Apoptosis Via PI3K/Akt Signaling Pathway In Osteosarcoma Cells.

Yuying ZhangQianqian ZhangJie BaoJintian HuangJun-Sheng Zhang
Published in: OncoTargets and therapy (2019)
Apiosporamide effectively suppressed MG63 cells proliferation by inducing apoptosis through PI3K/Akt and caspase-associated apoptotic pathway.
Keyphrases
  • cell cycle arrest
  • pi k akt
  • signaling pathway
  • induced apoptosis
  • cell death
  • cell proliferation
  • epithelial mesenchymal transition
  • endoplasmic reticulum stress
  • oxidative stress
  • anti inflammatory