Nasal Delivery of Haemophilus haemolyticus Is Safe, Reduces Influenza Severity, and Prevents Development of Otitis Media in Mice.

Naomi ScottKelly M MartinovichCaitlyn M GranlandElke J SeppanenM Christian TjiamCamilla de GierEdison FooKirsty R ShortKeng Yih ChewAlma FulurijaDeborah H StricklandPeter C RichmondLea-Ann S Kirkham

Published in: The Journal of infectious diseases (2024)

Haemophilus haemolyticus has potential as a live biotherapeutic for prevention or early treatment of influenza and influenza-driven NTHi OM. Additional studies will deem whether these findings translate to humans and other respiratory infections.

Keyphrases

adipose tissue
combination therapy
insulin resistance
replacement therapy
smoking cessation
chronic rhinosinusitis