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Multiple myeloma with plasmacytoma of the clivus bone presenting with multiple cranial nerve III, IV, and VI palsy: A diagnostic dilemma.

Chiranjiwi Prasad ShahRajan ChamlagainSangam ShahSubodh PaudelSanjit Kumar SahBipin KoiralaKamal PanditSanjeeta SitaulaAnjan Shrestha
Published in: Clinical case reports (2023)
Central nervous system (CNS) manifestation with cranial nerve palsy in multiple myeloma (MM) is a rare manifestation. Plasmacytoma originates from the bones of the skull base in 3% patients with MM but rarely develops from the soft tissues of the nasal cavity and paranasal sinuses. Here, we present a case of 68-year-old male patient with multiple myeloma, clivus bone plasmacytoma, and cavernous sinus syndrome.
Keyphrases
  • multiple myeloma
  • case report
  • bone mineral density
  • soft tissue
  • peripheral nerve
  • bone loss
  • gene expression
  • blood brain barrier
  • bone regeneration
  • cerebrospinal fluid
  • chronic rhinosinusitis