Recycling machinery of integrin coupled with focal adhesion turnover via RAB11-UNC13D-FAK axis for migration of pancreatic cancer cells.
Van-Thanh DuongMihyang HaJayoung KimJi-Young KimSiyoung ParkKhatun Mst ReshmaMyoung-Eun HanDongjun LeeYun Hak KimSae-Ock OhPublished in: Journal of translational medicine (2024)
We highlight that UNC13D, a novel prognostic factor, promotes pancreatic cancer progression by coupling integrin recycling with focal adhesion turnover via the RAB11-UNC13D-FAK axis for the migration of pancreatic cancer cells.