Adam E Handel (Adam Handel)

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 21

Top Topics

Hodgkin Lymphoma

Cerebrospinal Fluid

Gene Expression

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Journal of neurology, neurosurgery, and psychiatry

Science advances

Brain : a journal of neurology

This page only lists publications with an associated author ORCID identifier.

Publications

Jakob Theorell, Ruby Harrison, Robyn Williams, Matthew I J Raybould, Meng Zhao, Hannah Fox, Andrew Fower, Georgina Miller, Zoe Wu, Eleanor Browne, Victor Mgbachi, Bo Sun, Rohini Mopuri, Ying Li, Patrick Waters, Charlotte M Deane, Adam E Handel, Mateusz Makuch, Sarosh R Irani
Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Jakob Theorell, Ruby Harrison, Robyn Williams, Matthew I J Raybould, Meng Zhao, Hannah Fox, Andrew Fower, Georgina Miller, Zoe Wu, Eleanor Browne, Victor Mgbachi, Bo Sun, Rohini Mopuri, Ying Li, Patrick Waters, Charlotte M Deane, Adam E Handel, Mateusz Makuch, Sarosh R Irani
Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Jakob Theorell, Ruby Harrison, Robyn Williams, Matthew I J Raybould, Meng Zhao, Hannah Fox, Andrew Fower, Georgina Miller, Zoe Wu, Eleanor Browne, Victor Mgbachi, Bo Sun, Rohini Mopuri, Ying Li, Patrick Waters, Charlotte M Deane, Adam E Handel, Mateusz Makuch, Sarosh R Irani
Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Jakob Theorell, Ruby Harrison, Robyn Williams, Matthew I J Raybould, Meng Zhao, Hannah Fox, Andrew Fower, Georgina Miller, Zoe Wu, Eleanor Browne, Victor Mgbachi, Bo Sun, Rohini Mopuri, Ying Li, Patrick Waters, Charlotte M Deane, Adam E Handel, Mateusz Makuch, Sarosh R Irani
Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Jakob Theorell, Ruby Harrison, Robyn Williams, Matthew I J Raybould, Meng Zhao, Hannah Fox, Andrew Fower, Georgina Miller, Zoe Wu, Eleanor Browne, Victor Mgbachi, Bo Sun, Rohini Mopuri, Ying Li, Patrick Waters, Charlotte M Deane, Adam E Handel, Mateusz Makuch, Sarosh R Irani
Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Jakob Theorell, Ruby Harrison, Robyn Williams, Matthew I J Raybould, Meng Zhao, Hannah Fox, Andrew Fower, Georgina Miller, Zoe Wu, Eleanor Browne, Victor Mgbachi, Bo Sun, Rohini Mopuri, Ying Li, Patrick Waters, Charlotte M Deane, Adam E Handel, Mateusz Makuch, Sarosh R Irani
Ultrahigh frequencies of peripherally matured LGI1- and CASPR2-reactive B cells characterize the cerebrospinal fluid in autoimmune encephalitis. Proceedings of the National Academy of Sciences of the United States of America 121 (7) (2024)
Beth Lucas, Andrea J White, Fabian Klein, Clara Veiga-Villauriz, Adam E Handel, Andrea Bacon, Emilie J Cosway, Kieran D James, Sonia M Parnell, Izumi Ohigashi, Yousuke Takahama, William E Jenkinson, Georg A Hollander, Wei-Yu Lu, Graham Anderson
Embryonic keratin19 + progenitors generate multiple functionally distinct progeny to maintain epithelial diversity in the adult thymus medulla. Nature communications 14 (1) (2023)
Jonathan Cleaver, Katie Jeffery, Paul Klenerman, Ming Lim, Lahiru Handunnetthi, Sarosh R Irani, Adam E Handel
The immunobiology of herpes simplex virus encephalitis and post-viral autoimmunity. Brain : a journal of neurology (2023)
Valentina Damato, Jakob Theorell, Adam Al-Diwani, Anne Kathrin Kienzler, Mateusz Makuch, Bo Sun, Adam E Handel, Deniz Akdeniz, Antonio Berretta, Sudarshini Ramanathan, Andrew Fower, Daniel Whittam, Emily Gibbons, Nicholas McGlashan, Edward D Green, Saif Huda, Mark Woodhall, Jacqueline Palace, Fintan Sheerin, Patrick Waters, Maria I Leite, Anu Jacob, Sarosh R Irani
Rituximab abrogates aquaporin-4-specific germinal center activity in patients with neuromyelitis optica spectrum disorders. Proceedings of the National Academy of Sciences of the United States of America 119 (24) (2022)
Jimena Monzón-Sandoval, Elena Burlacu, Devika Agarwal, Adam E Handel, Liting Wei, John Davis, Sally A Cowley, M Zameel Cader, Caleb Webber
Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models. Disease models & mechanisms 15 (10) (2022)
Adam E Handel, Stanley Cheuk, Fatima Dhalla, Stefano Maio, Tania Hübscher, Ioanna A Rota, Mary E Deadman, Olov Ekwall, Matthias P Lutolf, Kenneth Weinberg, Georg A Hollander
Developmental dynamics of the neural crest-mesenchymal axis in creating the thymic microenvironment. Science advances 8 (19) (2022)
Adam Al-Diwani, Jakob Theorell, Valentina Damato, Joshua A Bull, Nicholas McGlashan, Edward Green, Anne Kathrin Kienzler, Ruby Harrison, Tasneem Hassanali, Leticia Campo, Molly Browne, Alistair Easton, Hooman Soleymani Majd, Keiko Tenaka, Raffaele Iorio, Russell C Dale, Paul J Harrison, John R Geddes, Digby J Quested, David Sharp, Soon Tae Lee, David W Nauen, Mateusz Makuch, Belinda R Lennox, Darren Fowler, Fintan Sheerin, Patrick J Waters, Maria Isabel Leite, Adam E Handel, Sarosh R Irani
Cervical lymph nodes and ovarian teratomas as germinal centres in NMDA receptor-antibody encephalitis. Brain : a journal of neurology 145 (8) (2022)
Ioanna A Rota, Adam E Handel, Stefano Maio, Fabian Klein, Fatima Dhalla, Mary E Deadman, Stanley Cheuk, Joseph A Newman, Yale S Michaels, Saulius Zuklys, Nicolas Prevot, Philip Hublitz, Philip D Charles, Athina Soragia Gkazi, Eleni Adamopoulou, Waseem Qasim, Edward Graham Davies, Imelda Hanson, Alistair T Pagnamenta, Carme Camps, Helene M Dreau, Andrea White, Kieran D James, Roman Fischer, Opher Gileadi, Jenny C Taylor, Tudor A Fulga, B Christoffer Lagerholm, Graham Anderson, Erdinc Sezgin, Georg A Hollander
FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency. Science advances 7 (49) (2021)
Samuel Pace, Michael Orrell, Mark Woodhall, Jacqueline Palace, Maria Isabel Leite, Sarosh R Irani, Patrick J Waters, Adam E Handel
Frequency of MOG-IgG in cerebrospinal fluid versus serum. Journal of neurology, neurosurgery, and psychiatry (2021)
Bergithe Eikeland Oftedal, Stefano Maio, Adam E Handel, Madeleine P J White, Duncan Howie, Simon Davis, Nicolas Prevot, Ioanna A Rota, Mary E Deadman, Benedikt Mathias Kessler, Roman Fischer, Nikolaus S Trede, Erdinc Sezgin, Rick M Maizels, Georg A Hollander
The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function. Communications biology 4 (1) (2021)
Thomas Barthlott, Adam E Handel, Hong Ying Teh, Rushika C Wirasinha, Katrin Hafen, Saulius Žuklys, Benoit Roch, Stuart H Orkin, Jean Pierre de Villartay, Stephen R Daley, Georg A Hollander
Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2. Nature communications 12 (1) (2021)
Ronan N McGinty, Adam E Handel, Teresa Moloney, Archana Ramesh, Andrew Fower, Emma Torzillo, Holger Kramer, Stephen Howell, Patrick J Waters, Jane Adcock, Arjune Sen, Bethan Lang, Sarosh R Irani
Clinical features which predict neuronal surface autoantibodies in new-onset focal epilepsy: implications for immunotherapies. Journal of neurology, neurosurgery, and psychiatry 92 (3) (2020)
Jeanette Baran-Gale, Michael D Morgan, Stefano Maio, Fatima Dhalla, Irene Calvo-Asensio, Mary E Deadman, Adam E Handel, Ashley Maynard, Steven Chen, Foad Green, Rene V Sit, Norma F Neff, Spyros Darmanis, Weilun Tan, Andy P May, John C Marioni, Chris Paul Ponting, Georg A Hollander
Ageing compromises mouse thymus function and remodels epithelial cell differentiation. eLife 9 (2020)
Fabiola Curion, Adam E Handel, Moustafa Attar, Giuseppe Gallone, Rory Bowden, M Zameel Cader, Michael B Clark
Targeted RNA sequencing enhances gene expression profiling of ultra-low input samples. RNA biology 17 (12) (2020)
Adam E Handel, Georg A Hollander
Comment on "Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells". Journal of immunology (Baltimore, Md. : 1950) 203 (9) (2020)
Piero Alberti, Adam E Handel
The contribution of thymic tolerance to central nervous system autoimmunity. Seminars in immunopathology 43 (1) (2020)