Benedikt Mathias Kessler (Benedikt Kessler, B M Kessler, Benedikt M Kessler)

Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 81

Top Venues

Nature immunology

Nature communications

Science (New York, N.Y.)

Proceedings of the National Academy of Sciences of the United States of America

University of Oxford

Ludwig Institute for Cancer Research Lausanne Branch of Immunology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Oxford Nov 01 2014

United Kingdom

Professor of Biochemistry and Life Science Mass Spectrometry :: Nuffield Department of Medicine

University of Oxford Nov 01 2014

United Kingdom

Professor of Biochemistry and Life Science Mass Spectrometry :: Nuffield Department of Medicine

Education History

Ludwig Institute for Cancer Research Lausanne Branch of Immunology Nov 01 1993 - Apr 01 1998

Switzerland

PHD :: University of Lausanne / LICR

Publications

Megat H B A Hamid, Pablo F Céspedes, Chen Jin, Ji-Li Chen, Uzi Gileadi, Elie Antoun, Zhu Liang, Fei Gao, Renuka Teague, Nikita Manoharan, David Maldonado-Perez, Nasullah Khalid-Alham, Lucia Cerundolo, Raul Ciaoca, Svenja S Hester, Adán Pinto-Fernández, Simeon D Draganov, Iolanda Vendrell, Guihai Liu, Xuan Yao, Audun Kvalvaag, Delaney C C Dominey-Foy, Charunya Nanayakkara, Nikolaos I Kanellakis, Yi-Ling Chen, Craig Waugh, Sally-Ann Clark, Kevin Clark, Paul Sopp, Najib M Rahman, Clare Verrill, Benedikt Mathias Kessler, Graham Ogg, Ricardo A Fernandes, Roman Fischer, Yanchun Peng, Michael L Dustin, Tao Dong
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity. Nature immunology (2024)
Megat H B A Hamid, Pablo F Céspedes, Chen Jin, Ji-Li Chen, Uzi Gileadi, Elie Antoun, Zhu Liang, Fei Gao, Renuka Teague, Nikita Manoharan, David Maldonado-Perez, Nasullah Khalid-Alham, Lucia Cerundolo, Raul Ciaoca, Svenja S Hester, Adán Pinto-Fernández, Simeon D Draganov, Iolanda Vendrell, Guihai Liu, Xuan Yao, Audun Kvalvaag, Delaney C C Dominey-Foy, Charunya Nanayakkara, Nikolaos I Kanellakis, Yi-Ling Chen, Craig Waugh, Sally-Ann Clark, Kevin Clark, Paul Sopp, Najib M Rahman, Clare Verrill, Benedikt Mathias Kessler, Graham Ogg, Ricardo A Fernandes, Roman Fischer, Yanchun Peng, Michael L Dustin, Tao Dong
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity. Nature immunology 25 (5) (2024)
Cyriel S Olie, Darragh P O'Brien, Hannah B L Jones, Zhu Liang, Andreas Damianou, Ilknur Sur-Erdem, Adán Pinto-Fernández, Vered Raz, Benedikt Mathias Kessler
Deubiquitinases in muscle physiology and disorders. Biochemical Society transactions 52 (3) (2024)
Cyriel S Olie, Darragh P O'Brien, Hannah B L Jones, Zhu Liang, Andreas Damianou, Ilknur Sur-Erdem, Adán Pinto-Fernández, Vered Raz, Benedikt Mathias Kessler
Deubiquitinases in muscle physiology and disorders. Biochemical Society transactions 52 (3) (2024)
Megat H B A Hamid, Pablo F Céspedes, Chen Jin, Ji-Li Chen, Uzi Gileadi, Elie Antoun, Zhu Liang, Fei Gao, Renuka Teague, Nikita Manoharan, David Maldonado-Perez, Nasullah Khalid-Alham, Lucia Cerundolo, Raul Ciaoca, Svenja S Hester, Adán Pinto-Fernández, Simeon D Draganov, Iolanda Vendrell, Guihai Liu, Xuan Yao, Audun Kvalvaag, Delaney C C Dominey-Foy, Charunya Nanayakkara, Nikolaos I Kanellakis, Yi-Ling Chen, Craig Waugh, Sally-Ann Clark, Kevin Clark, Paul Sopp, Najib M Rahman, Clare Verrill, Benedikt Mathias Kessler, Graham Ogg, Ricardo A Fernandes, Roman Fischer, Yanchun Peng, Michael L Dustin, Tao Dong
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity. Nature immunology 25 (5) (2024)
Ryan D Imhoff, Rishi Patel, Muhammad Hassan Safdar, Hannah B L Jones, Adan Pinto-Fernandez, Iolanda Vendrell, Hao Chen, Christine S Muli, Aaron D Krabill, Benedikt Mathias Kessler, Michael K Wendt, Chittaranjan Das, Daniel P Flaherty
Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1. Journal of medicinal chemistry (2024)
Hongbin Yang, Shahd Fouad, Paul Smith, Eun Young Bae, Yu Ji, Xinhui Lan, Ava Van Ess, Francesca M Buffa, Roman Fischer, Iolanda Vendrell, Benedikt Mathias Kessler, Vincenzo D'Angiolella
Cyclin F-EXO1 axis controls cell cycle-dependent execution of double-strand break repair. Science advances 10 (32) (2024)
Cyriel S Olie, Darragh P O'Brien, Hannah B L Jones, Zhu Liang, Andreas Damianou, Ilknur Sur-Erdem, Adán Pinto-Fernández, Vered Raz, Benedikt Mathias Kessler
Deubiquitinases in muscle physiology and disorders. Biochemical Society transactions (2024)
Ryan D Imhoff, Rishi Patel, Muhammad Hassan Safdar, Hannah B L Jones, Adan Pinto-Fernandez, Iolanda Vendrell, Hao Chen, Christine S Muli, Aaron D Krabill, Benedikt Mathias Kessler, Michael K Wendt, Chittaranjan Das, Daniel P Flaherty
Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1. Journal of medicinal chemistry 67 (6) (2024)
Andreas Damianou, Zhu Liang, Frederik Lassen, Iolanda Vendrell, George Vere, Svenja Hester, Philip D Charles, Adan Pinto-Fernandez, Alberto Santos, Roman Fischer, Benedikt Mathias Kessler
Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex. Life science alliance 7 (5) (2024)
Andreas Damianou, Zhu Liang, Frederik Lassen, Iolanda Vendrell, George Vere, Svenja Hester, Philip D Charles, Adan Pinto-Fernandez, Alberto Santos, Roman Fischer, Benedikt Mathias Kessler
Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex. Life science alliance 7 (5) (2024)
Hongbin Yang, Shahd Fouad, Paul Smith, Eun Young Bae, Yu Ji, Xinhui Lan, Ava Van Ess, Francesca M Buffa, Roman Fischer, Iolanda Vendrell, Benedikt Mathias Kessler, Vincenzo D'Angiolella
Cyclin F-EXO1 axis controls cell cycle-dependent execution of double-strand break repair. Science advances 10 (32) (2024)
Andreas Damianou, Zhu Liang, Frederik Lassen, Iolanda Vendrell, George Vere, Svenja Hester, Philip D Charles, Adan Pinto-Fernandez, Alberto Santos, Roman Fischer, Benedikt Mathias Kessler
Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex. Life science alliance 7 (5) (2024)
Hongbin Yang, Shahd Fouad, Paul Smith, Eun Young Bae, Yu Ji, Xinhui Lan, Ava Van Ess, Francesca M Buffa, Roman Fischer, Iolanda Vendrell, Benedikt Mathias Kessler, Vincenzo D'Angiolella
Cyclin F-EXO1 axis controls cell cycle-dependent execution of double-strand break repair. Science advances 10 (32) (2024)
Megat H B A Hamid, Pablo F Céspedes, Chen Jin, Ji-Li Chen, Uzi Gileadi, Elie Antoun, Zhu Liang, Fei Gao, Renuka Teague, Nikita Manoharan, David Maldonado-Perez, Nasullah Khalid-Alham, Lucia Cerundolo, Raul Ciaoca, Svenja S Hester, Adán Pinto-Fernández, Simeon D Draganov, Iolanda Vendrell, Guihai Liu, Xuan Yao, Audun Kvalvaag, Delaney C C Dominey-Foy, Charunya Nanayakkara, Nikolaos I Kanellakis, Yi-Ling Chen, Craig Waugh, Sally-Ann Clark, Kevin Clark, Paul Sopp, Najib M Rahman, Clare Verrill, Benedikt Mathias Kessler, Graham Ogg, Ricardo A Fernandes, Roman Fischer, Yanchun Peng, Michael L Dustin, Tao Dong
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity. Nature immunology (2024)
Ryan D Imhoff, Rishi Patel, Muhammad Hassan Safdar, Hannah B L Jones, Adan Pinto-Fernandez, Iolanda Vendrell, Hao Chen, Christine S Muli, Aaron D Krabill, Benedikt Mathias Kessler, Michael K Wendt, Chittaranjan Das, Daniel P Flaherty
Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1. Journal of medicinal chemistry 67 (6) (2024)
Andrea Stieger, Markus Huber, Zhanru Yu, Benedikt Mathias Kessler, Roman Fischer, Lukas Andereggen, Beatrice Kobel, Frank Stueber, Markus Martin Luedi, Mark G Filipovic
Association of Indoleamine 2,3-Dioxygenase (IDO) Activity with Outcome after Cardiac Surgery in Adult Patients. Metabolites 14 (6) (2024)
Cyriel S Olie, Darragh P O'Brien, Hannah B L Jones, Zhu Liang, Andreas Damianou, Ilknur Sur-Erdem, Adán Pinto-Fernández, Vered Raz, Benedikt Mathias Kessler
Deubiquitinases in muscle physiology and disorders. Biochemical Society transactions 52 (3) (2024)
Andreas Damianou, Zhu Liang, Frederik Lassen, Iolanda Vendrell, George Vere, Svenja Hester, Philip D Charles, Adan Pinto-Fernandez, Alberto Santos, Roman Fischer, Benedikt Mathias Kessler
Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex. Life science alliance 7 (5) (2024)
Andrea Stieger, Markus Huber, Zhanru Yu, Benedikt Mathias Kessler, Roman Fischer, Lukas Andereggen, Beatrice Kobel, Frank Stueber, Markus Martin Luedi, Mark G Filipovic
Association of Indoleamine 2,3-Dioxygenase (IDO) Activity with Outcome after Cardiac Surgery in Adult Patients. Metabolites 14 (6) (2024)
Andreas Damianou, Zhu Liang, Frederik Lassen, Iolanda Vendrell, George Vere, Svenja Hester, Philip D Charles, Adan Pinto-Fernandez, Alberto Santos, Roman Fischer, Benedikt Mathias Kessler
Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex. Life science alliance 7 (5) (2024)
Andreas Damianou, Zhu Liang, Frederik Lassen, Iolanda Vendrell, George Vere, Svenja Hester, Philip D Charles, Adan Pinto-Fernandez, Alberto Santos, Roman Fischer, Benedikt Mathias Kessler
Oncogenic mutations of KRAS modulate its turnover by the CUL3/LZTR1 E3 ligase complex. Life science alliance 7 (5) (2024)
Megat H B A Hamid, Pablo F Céspedes, Chen Jin, Ji-Li Chen, Uzi Gileadi, Elie Antoun, Zhu Liang, Fei Gao, Renuka Teague, Nikita Manoharan, David Maldonado-Perez, Nasullah Khalid-Alham, Lucia Cerundolo, Raul Ciaoca, Svenja S Hester, Adán Pinto-Fernández, Simeon D Draganov, Iolanda Vendrell, Guihai Liu, Xuan Yao, Audun Kvalvaag, Delaney C C Dominey-Foy, Charunya Nanayakkara, Nikolaos I Kanellakis, Yi-Ling Chen, Craig Waugh, Sally-Ann Clark, Kevin Clark, Paul Sopp, Najib M Rahman, Clare Verrill, Benedikt Mathias Kessler, Graham Ogg, Ricardo A Fernandes, Roman Fischer, Yanchun Peng, Michael L Dustin, Tao Dong
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity. Nature immunology 25 (5) (2024)
Megat H B A Hamid, Pablo F Céspedes, Chen Jin, Ji-Li Chen, Uzi Gileadi, Elie Antoun, Zhu Liang, Fei Gao, Renuka Teague, Nikita Manoharan, David Maldonado-Perez, Nasullah Khalid-Alham, Lucia Cerundolo, Raul Ciaoca, Svenja S Hester, Adán Pinto-Fernández, Simeon D Draganov, Iolanda Vendrell, Guihai Liu, Xuan Yao, Audun Kvalvaag, Delaney C C Dominey-Foy, Charunya Nanayakkara, Nikolaos I Kanellakis, Yi-Ling Chen, Craig Waugh, Sally-Ann Clark, Kevin Clark, Paul Sopp, Najib M Rahman, Clare Verrill, Benedikt Mathias Kessler, Graham Ogg, Ricardo A Fernandes, Roman Fischer, Yanchun Peng, Michael L Dustin, Tao Dong
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity. Nature immunology 25 (5) (2024)
Hongbin Yang, Shahd Fouad, Paul Smith, Eun Young Bae, Yu Ji, Xinhui Lan, Ava Van Ess, Francesca M Buffa, Roman Fischer, Iolanda Vendrell, Benedikt Mathias Kessler, Vincenzo D'Angiolella
Cyclin F-EXO1 axis controls cell cycle-dependent execution of double-strand break repair. Science advances 10 (32) (2024)
Kang Zhu, Chatrin Chatrin, Marcin Józef Suskiewicz, Vincent Aucagne, Benjamin M Foster, Benedikt Mathias Kessler, Ian Gibbs-Seymour, Dragana Ahel, Ivan Ahel
Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L. EMBO reports (2024)
Megat H B A Hamid, Pablo F Céspedes, Chen Jin, Ji-Li Chen, Uzi Gileadi, Elie Antoun, Zhu Liang, Fei Gao, Renuka Teague, Nikita Manoharan, David Maldonado-Perez, Nasullah Khalid-Alham, Lucia Cerundolo, Raul Ciaoca, Svenja S Hester, Adán Pinto-Fernández, Simeon D Draganov, Iolanda Vendrell, Guihai Liu, Xuan Yao, Audun Kvalvaag, Delaney C C Dominey-Foy, Charunya Nanayakkara, Nikolaos I Kanellakis, Yi-Ling Chen, Craig Waugh, Sally-Ann Clark, Kevin Clark, Paul Sopp, Najib M Rahman, Clare Verrill, Benedikt Mathias Kessler, Graham Ogg, Ricardo A Fernandes, Roman Fischer, Yanchun Peng, Michael L Dustin, Tao Dong
Unconventional human CD61 pairing with CD103 promotes TCR signaling and antigen-specific T cell cytotoxicity. Nature immunology 25 (5) (2024)
Andrea Stieger, Markus Huber, Zhanru Yu, Benedikt Mathias Kessler, Roman Fischer, Lukas Andereggen, Beatrice Kobel, Frank Stueber, Markus Martin Luedi, Mark G Filipovic
Association of Indoleamine 2,3-Dioxygenase (IDO) Activity with Outcome after Cardiac Surgery in Adult Patients. Metabolites 14 (6) (2024)
Larissa Dietz, Cara J Ellison, Carlos Riechmann, C Keith Cassidy, F Daniel Felfoldi, Adan Pinto-Fernandez, Benedikt Mathias Kessler, Paul R Elliott
Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6. Science (New York, N.Y.) 379 (6637) (2023)
Dedrick Kok Hong Chan, Amit K Mandal, Svenja Hester, Zhanru Yu, Geoff Stuart Higgins, Benedikt Mathias Kessler, Roman Fischer, Simon James Alexander Buczacki
Biallelic FBXW7 knockout induces AKAP8-mediated DNA damage in neighbouring wildtype cells. Cell death discovery 9 (1) (2023)
Larissa Dietz, Cara J Ellison, Carlos Riechmann, C Keith Cassidy, F Daniel Felfoldi, Adan Pinto-Fernandez, Benedikt Mathias Kessler, Paul R Elliott
Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6. Science (New York, N.Y.) 379 (6637) (2023)
Dedrick Kok Hong Chan, Amit K Mandal, Svenja Hester, Zhanru Yu, Geoff Stuart Higgins, Benedikt Mathias Kessler, Roman Fischer, Simon James Alexander Buczacki
Biallelic FBXW7 knockout induces AKAP8-mediated DNA damage in neighbouring wildtype cells. Cell death discovery 9 (1) (2023)
Frederik H Lassen, Samvida S Venkatesh, Nikolas A Baya, Wei Zhou, Alex Bloemendal, Benjamin M Neale, Benedikt Mathias Kessler, Nicola Whiffin, Cecilia M Lindgren, Duncan S Palmer
Exome-wide evidence of compound heterozygous effects across common phenotypes in the UK Biobank. medRxiv : the preprint server for health sciences (2023)
Larissa Dietz, Cara J Ellison, Carlos Riechmann, C Keith Cassidy, F Daniel Felfoldi, Adan Pinto-Fernandez, Benedikt Mathias Kessler, Paul R Elliott
Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6. Science (New York, N.Y.) (2023)
Jin Gan, Adán Pinto-Fernández, Dennis Flierman, Jimmy J L L Akkermans, Darragh P O'Brien, Helene Greenwood, Hannah Claire Scott, Günter Fritz, Klaus-Peter Knobeloch, Jacques Neefjes, Hans van Dam, Huib Ovaa, Hidde L Ploegh, Benedikt Mathias Kessler, Paul P Geurink, Aysegul Sapmaz
USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism. Proceedings of the National Academy of Sciences of the United States of America 120 (50) (2023)
Larissa Dietz, Cara J Ellison, Carlos Riechmann, C Keith Cassidy, F Daniel Felfoldi, Adan Pinto-Fernandez, Benedikt Mathias Kessler, Paul R Elliott
Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6. Science (New York, N.Y.) 379 (6637) (2023)
Larissa Dietz, Cara J Ellison, Carlos Riechmann, C Keith Cassidy, F Daniel Felfoldi, Adan Pinto-Fernandez, Benedikt Mathias Kessler, Paul R Elliott
Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6. Science (New York, N.Y.) 379 (6637) (2023)
Larissa Dietz, Cara J Ellison, Carlos Riechmann, C Keith Cassidy, F Daniel Felfoldi, Adan Pinto-Fernandez, Benedikt Mathias Kessler, Paul R Elliott
Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6. Science (New York, N.Y.) 379 (6637) (2023)
Simon Davis, Connor Scott, Janina Oetjen, Philip D Charles, Benedikt Mathias Kessler, Olaf Ansorge, Roman Fischer
Deep topographic proteomics of a human brain tumour. Nature communications 14 (1) (2023)
Cyriel Sebastiaan Olie, Adan Pinto-Fernandez, Andreas Damianou, Iolanda Vendrell, Hailiang Mei, Bianca den Hamer, Erik van der Wal, Jessica C de Greef, Vered Raz, Benedikt Mathias Kessler
USP18 is an essential regulator of muscle cell differentiation and maturation. Cell death & disease 14 (3) (2023)
Hannah C Scott, Simeon D Draganov, Zhanru Yu, Benedikt Mathias Kessler, Adan Pinto-Fernandez
Targeted Mass Spectrometry Reveals Interferon-Dependent Eicosanoid and Fatty Acid Alterations in Chronic Myeloid Leukaemia. International journal of molecular sciences 24 (21) (2023)
Tehmina Bharucha, Bevin Gangadharan, Abhinav Kumar, Ashleigh C Myall, Nazli Ayhan, Boris Pastorino, Anisone Chanthongthip, Manivanh Vongsouvath, Mayfong Mayxay, Onanong Sengvilaipaseuth, Ooyanong Phonemixay, Sayaphet Rattanavong, Darragh P O'Brien, Iolanda Vendrell, Roman Fischer, Benedikt Mathias Kessler, Lance Turtle, Xavier de Lamballerie, Audrey Dubot-Pérès, Paul N Newton, Nicole Zitzmann, null SEAe Consortium
Deep Proteomics Network and Machine Learning Analysis of Human Cerebrospinal Fluid in Japanese Encephalitis Virus Infection. Journal of proteome research (2023)
Cyriel Sebastiaan Olie, Adan Pinto-Fernandez, Andreas Damianou, Iolanda Vendrell, Hailiang Mei, Bianca den Hamer, Erik van der Wal, Jessica C de Greef, Vered Raz, Benedikt Mathias Kessler
USP18 is an essential regulator of muscle cell differentiation and maturation. Cell death & disease 14 (3) (2023)
Dedrick Kok Hong Chan, Amit K Mandal, Svenja Hester, Zhanru Yu, Geoff Stuart Higgins, Benedikt Mathias Kessler, Roman Fischer, Simon James Alexander Buczacki
Biallelic FBXW7 knockout induces AKAP8-mediated DNA damage in neighbouring wildtype cells. Cell death discovery 9 (1) (2023)
Zhuoyao Chen, Rafael M Ioris, Stacey Richardson, Ava N Van Ess, Iolanda Vendrell, Benedikt Mathias Kessler, Francesca M Buffa, Luca Busino, Steven C Clifford, Alex N Bullock, Vincenzo D'Angiolella
Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation. Cell death and differentiation 29 (10) (2022)
Darragh P O'Brien, Adam M Thorne, Honglei Huang, Elisa Pappalardo, Xuan Yao, Peter Søndergaard Thyrrestrup, Kristian Ravlo, Niels Secher, Rikke Norregaard, Rutger J Ploeg, Bente Jespersen, Benedikt Mathias Kessler
Integrative omics reveals subtle molecular perturbations following ischemic conditioning in a porcine kidney transplant model. Clinical proteomics 19 (1) (2022)
Hannah B L Jones, Raphael Heilig, Simon Davis, Roman Fischer, Benedikt Mathias Kessler, Adan Pinto-Fernandez
ABPP-HT*-Deep Meets Fast for Activity-Based Profiling of Deubiquitylating Enzymes Using Advanced DIA Mass Spectrometry Methods. International journal of molecular sciences 23 (6) (2022)
George Vere, Md Rashadul Alam, Sam Farrar, Rachel Kealy, Benedikt Mathias Kessler, Darragh P O'Brien, Adán Pinto-Fernández
Targeting the Ubiquitylation and ISGylation Machinery for the Treatment of COVID-19. Biomolecules 12 (2) (2022)
L Leonie van Leeuwen, Nora A Spraakman, Aukje Brat, Honglei Huang, Adam M Thorne, Sarah Bonham, Bas W M van Balkom, Rutger Jan Ploeg, Benedikt Mathias Kessler, Hendrik Gerrit Derk Leuvenink
Proteomic analysis of machine perfusion solution from brain dead donor kidneys reveals that elevated complement, cytoskeleton and lipid metabolism proteins are associated with 1-year outcome. Transplant international : official journal of the European Society for Organ Transplantation 34 (9) (2021)
Ann-Marie K Shorrocks, Samuel E Jones, Kaima Tsukada, Carl A Morrow, Zoulikha Belblidia, Johanna Shen, Iolanda Vendrell, Roman Fischer, Benedikt Mathias Kessler, Andrew N Blackford
The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks. Nature communications 12 (1) (2021)
Emily Feneberg, Philip D Charles, Mattéa J Finelli, Connor Scott, Benedikt Mathias Kessler, Roman Fischer, Olaf Ansorge, Elizabeth Gray, Kevin Talbot, Matthew C Kiernan
Detection and quantification of novel C-terminal TDP-43 fragments in ALS-TDP. Brain pathology (Zurich, Switzerland) 31 (4) (2021)
Grigory Ryzhakov, Hannah Almuttaqi, Alastair L Corbin, Dorothée Lisa Berthold, Tariq E Khoyratty, Hayley L Eames, Samuel Bullers, Claire Pearson, Zhichao Ai, Kristina Zec, Sarah Bonham, Roman Fischer, Luke Jostins-Dean, Simon P L Travis, Benedikt Mathias Kessler, Irina A Udalova
Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation. Nature communications 12 (1) (2021)
E Josue Ruiz, Adan Pinto-Fernandez, Andrew P Turnbull, Linxiang Lan, Thomas M Charlton, Hannah C Scott, Andreas Damianou, George Vere, Eva M Riising, Clive Da Costa, Wojciech W Krajewski, David Guerin, Jeffrey D Kearns, Stephanos Ioannidis, Marie Katz, Crystal McKinnon, Jonathan O'Connell, Natalia Moncaut, Ian Rosewell, Emma Nye, Neil Jones, Claire Heride, Malte Gersch, Min Wu, Christopher J Dinsmore, Tim R Hammonds, Sunkyu Kim, David Komander, Sylvie Urbe, Michael J Clague, Benedikt Mathias Kessler, Axel Behrens
USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma. eLife 10 (2021)
Bergithe Eikeland Oftedal, Stefano Maio, Adam E Handel, Madeleine P J White, Duncan Howie, Simon Davis, Nicolas Prevot, Ioanna A Rota, Mary E Deadman, Benedikt Mathias Kessler, Roman Fischer, Nikolaus S Trede, Erdinc Sezgin, Rick M Maizels, Georg A Hollander
The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function. Communications biology 4 (1) (2021)
Deeksha Munnur, Qiwen Teo, Denzel Eggermont, Horace H Y Lee, Fabien Thery, Julian Ho, Sophie Wilhelmina van Leur, Wilson W S Ng, Lewis Y L Siu, Antje Beling, Hidde Ploegh, Adan Pinto-Fernandez, Andreas Damianou, Benedikt Mathias Kessler, Francis Impens, Chris Ka Pun Mok, Sumana Sanyal
Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection. Nature immunology 22 (11) (2021)
S Mark Wainwright, Ben R Hopkins, Cláudia C Mendes, Aashika Sekar, Benjamin Kroeger, Josephine E E U Hellberg, Shih-Jung Fan, Abigail Pavey, Pauline P Marie, Aaron Leiblich, Irem Sepil, Philip D Charles, Marie L Thézénas, Roman Fischer, Benedikt Mathias Kessler, Carina Gandy, Laura Corrigan, Rachel Patel, Stuart Wigby, John F Morris, Deborah C I Goberdhan, Clive Wilson
Drosophila Sex Peptide controls the assembly of lipid microcarriers in seminal fluid. Proceedings of the National Academy of Sciences of the United States of America 118 (5) (2021)
Benedikt Mathias Kessler
DUB esterase activity further decodes ubiquitin's enigma. Proceedings of the National Academy of Sciences of the United States of America 118 (6) (2021)
Marie-Laëtitia Thézénas, Bianca De Leo, Alexis Laux-Biehlmann, Cemsel Bafligil, Bernd Elger, Thomas Theodor Tapmeier, Karl Morten, Nilufer Rahmioglu, Stephanie G Dakin, Philip D Charles, Fernando Estrada Martinez, Graham Steers, Oliver M Fischer, Joerg Mueller, Holger Hess-Stumpp, Andreas Steinmeyer, Sanjiv Manek, Krina T Zondervan, Stephen Kennedy, Christian M Becker, Catherine Shang, Thomas M Zollner, Benedikt Mathias Kessler, Udo Oppermann
Author Correction: Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions. Scientific reports 10 (1) (2020)
Štefan Bálint, Sabina Müller, Roman Fischer, Benedikt Mathias Kessler, Maria Harkiolaki, Salvatore Valitutti, Michael L Dustin
Supramolecular attack particles are autonomous killing entities released from cytotoxic T cells. Science (New York, N.Y.) 368 (6493) (2020)
Emma J Fenech, Federica Lari, Philip D Charles, Roman Fischer, Marie Laétitia-Thézénas, Katrin Bagola, Adrienne W Paton, James C Paton, Mads Gyrd-Hansen, Benedikt Mathias Kessler, John C Christianson
Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling. eLife 9 (2020)
Yanchun Peng, Alexander J Mentzer, Guihai Liu, Xuan Yao, Zixi Yin, Danning Dong, Wanwisa Dejnirattisai, Timothy Rostron, Piyada Supasa, Chang Liu, Cesar López-Camacho, Jose Slon-Campos, Yuguang Zhao, David I Stuart, Guido C Paesen, Jonathan M Grimes, Alfred A Antson, Oliver W Bayfield, Dorothy E D P Hawkins, De-Sheng Ker, Beibei Wang, Lance Turtle, Krishanthi Subramaniam, Paul Thomson, Ping Zhang, Christina Dold, Jeremy Ratcliff, Peter Simmonds, Thushan de Silva, Paul Sopp, Dannielle Wellington, Ushani Rajapaksa, Yi-Ling Chen, Mariolina Salio, Giorgio Napolitani, Wayne Paes, Persephone Borrow, Benedikt Mathias Kessler, Jeremy W Fry, Nikolai F Schwabe, Malcolm Gracie Semple, J Kenneth Baillie, Shona C Moore, Peter J M Openshaw, M Azim Ansari, Susanna Dunachie, Eleanor Barnes, John Frater, Georgina Kerr, Philip Goulder, Teresa Lockett, Robert Levin, Yonghong Zhang, Ronghua Jing, Ling-Pei Ho, null null, null null, Richard J Cornall, Christopher P Conlon, Paul Klenerman, Gavin R Screaton, Juthathip Mongkolsapaya, Andrew McMichael, Julian C Knight, Graham Ogg, Tao Dong
Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19. Nature immunology 21 (11) (2020)
Adam M Thorne, Honglei Huang, Darragh P O'Brien, Marco Eijken, Nicoline Valentina Krogstrup, Rikke Norregaard, Bjarne Møller, Rutger J Ploeg, Bente Jespersen, Benedikt Mathias Kessler
Subclinical effects of remote ischaemic conditioning in human kidney transplants revealed by quantitative proteomics. Clinical proteomics 17 (1) (2020)
Martin Cusack, Hamish W King, Paolo Spingardi, Benedikt Mathias Kessler, Robert J Klose, Skirmantas Kriaucionis
Distinct contributions of DNA methylation and histone acetylation to the genomic occupancy of transcription factors. Genome research 30 (10) (2020)
John Fielden, Katherine Wiseman, Ignacio Torrecilla, Shudong Li, Samuel Hume, Shih-Chieh Chiang, Annamaria Ruggiano, Abhay Narayan Singh, Raimundo Freire, Sylvana Hassanieh, Enric Domingo, Iolanda Vendrell, Roman Fischer, Benedikt Mathias Kessler, Timothy S Maughan, Sherif F El-Khamisy, Kristijan Ramadan
TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts. Nature communications 11 (1) (2020)
Marie-Laëtitia Thézénas, Bianca De Leo, Alexis Laux-Biehlmann, Cemsel Bafligil, Bernd Elger, Thomas Theodor Tapmeier, Karl Morten, Nilufer Rahmioglu, Stephanie G Dakin, Philip D Charles, Fernando Estrada Martinez, Graham Steers, Oliver M Fischer, Joerg Mueller, Holger Hess-Stumpp, Andreas Steinmeyer, Sanjiv Manek, Krina T Zondervan, Stephen Kennedy, Christian M Becker, Catherine Shang, Thomas M Zollner, Benedikt Mathias Kessler, Udo Oppermann
Amine oxidase 3 is a novel pro-inflammatory marker of oxidative stress in peritoneal endometriosis lesions. Scientific reports 10 (1) (2020)
Irem Sepil, Ben R Hopkins, Rebecca Dean, Eleanor Bath, Solomon Friedman, Ben Swanson, Harrison J Ostridge, Lucy Harper, Norene A Buehner, Mariana Federica Wolfner, Rebecca Konietzny, Marie-Laëtitia Thézénas, Elizabeth Sandham, Philip D Charles, Roman Fischer, Josefa Steinhauer, Benedikt Mathias Kessler, Stuart Wigby
Male reproductive aging arises via multifaceted mating-dependent sperm and seminal proteome declines, but is postponable in Drosophila. Proceedings of the National Academy of Sciences of the United States of America 117 (29) (2020)
Ben R Hopkins, Irem Sepil, Sarah Bonham, Thomas Miller, Philip D Charles, Roman Fischer, Benedikt Mathias Kessler, Clive Wilson, Stuart Wigby
BMP signaling inhibition in Drosophila secondary cells remodels the seminal proteome and self and rival ejaculate functions. Proceedings of the National Academy of Sciences of the United States of America 116 (49) (2019)
Norbert Volkmar, Maria-Laetitia Thezenas, Sharon M Louie, Szymon Juszkiewicz, Daniel K Nomura, Ramanujan S Hegde, Benedikt Mathias Kessler, John C Christianson
The ER membrane protein complex promotes biogenesis of sterol-related enzymes maintaining cholesterol homeostasis. Journal of cell science 132 (2) (2019)
Ben R Hopkins, Irem Sepil, Marie-Laëtitia Thézénas, James F Craig, Thomas Miller, Philip D Charles, Roman Fischer, Benedikt Mathias Kessler, Amanda Bretman, Tommaso Pizzari, Stuart Wigby
Divergent allocation of sperm and the seminal proteome along a competition gradient in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America 116 (36) (2019)
Aurelia Stangl, Paul R Elliott, Adan Pinto-Fernandez, Sarah Bonham, Luke Harrison, Annalisa Schaub, Kerstin Kutzner, Kirstin Keusekotten, Paul Thomas Pfluger, Farid El Oualid, Benedikt Mathias Kessler, David Komander, Daniel Krappmann
Regulation of the endosomal SNX27-retromer by OTULIN. Nature communications 10 (1) (2019)
Carolin A Müller, Michael A Boemo, Paolo Spingardi, Benedikt Mathias Kessler, Skirmantas Kriaucionis, Jared T Simpson, Conrad A Nieduszynski
Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads. Nature methods 16 (5) (2019)
Aysegul Sapmaz, Ilana Berlin, Erik Bos, Ruud H Wijdeven, Hans Janssen, Rebecca Konietzny, Jimmy J Akkermans, Ayse Elif Erson-Bensan, Roman I Koning, Benedikt Mathias Kessler, Jacques Neefjes, Huib Ovaa
USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7. Nature communications 10 (1) (2019)
Saleta Vazquez-Rodriguez, Miranda Wright, Catherine M Rogers, Adam P Cribbs, Srikannathasan Velupillai, Martin Philpott, Henry Lee, James E Dunford, Kilian V M Huber, Matthew B Robers, James D Vasta, Marie-Laetitia Thezenas, Sarah Bonham, Benedikt Mathias Kessler, James Bennett, Oleg Fedorov, Florence Raynaud, Adam Donovan, Julian Blagg, Vassilios Bavetsias, Udo Oppermann, Chas Bountra, Akane Kawamura, Paul E Brennan
Design, Synthesis and Characterization of Covalent KDM5 Inhibitors. Angewandte Chemie (International ed. in English) 58 (2) (2018)
Tianyi Zhang, Guifeng Wei, Christopher J Millard, Roman Fischer, Rebecca Konietzny, Benedikt Mathias Kessler, John W R Schwabe, Neil Brockdorff
A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes. Nature communications 9 (1) (2018)
Jade Bailey, Simon Davis, Andrew Shaw, Marina Diotallevi, Roman Fischer, Matthew A Benson, Hanneng Zhu, James Brown, Shoumo Bhattacharya, Benedikt Mathias Kessler, Keith M Channon, Mark J Crabtree
Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation. Scientific reports 8 (1) (2018)
Suzana Markolovic, Qinqin Zhuang, Sarah E Wilkins, Charlotte D Eaton, Martine I Abboud, Maximiliano J Katz, Helen E McNeil, Robert K Leśniak, Charlotte Hall, Weston B Struwe, Rebecca Konietzny, Simon Davis, Ming Yang, Wei Ge, Justin L P Benesch, Benedikt Mathias Kessler, Peter J Ratcliffe, Matthew E Cockman, Roman Fischer, Pablo Wappner, Rasheduzzaman Chowdhury, Mathew L Coleman, Christopher J Schofield
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases. Nature chemical biology 14 (7) (2018)
Anna Motnenko, Chih-Chao Liang, Di Yang, David Lopez-Martinez, Yasunaga Yoshikawa, Bao Zhan, Katherine E Ward, Jiayang Tian, Wilhelm Haas, Paolo Spingardi, Benedikt Mathias Kessler, Skirmantas Kriaucionis, Steven P Gygi, Martin A Cohn
Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein. PLoS genetics 14 (10) (2018)
A E Yuzhalin, Alex N Gordon-Weeks, M L Tognoli, K Jones, Bosjtan Markelc, R Konietzny, Roman Fischer, A Muth, Eric O'Neill, P R Thompson, P J Venables, Benedikt Mathias Kessler, S Y Lim, R J Muschel
Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix. Nature communications 9 (1) (2018)
Ryotaro Nishi, Paul W G Wijnhoven, Yusuke Kimura, Misaki Matsui, Rebecca Konietzny, Qian Wu, Keisuke Nakamura, Thomas L Blundell, Benedikt Mathias Kessler
The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage. Scientific reports 8 (1) (2018)
Honglei Huang, Leon F A van Dullemen, Mohammed Z Akhtar, Maria-Letizia Lo Faro, Zhanru Yu, Alessandro Valli, Anthony Dona, Marie-Laëtitia Thézénas, Philip D Charles, Roman Fischer, Maria Kaisar, Henri G D Leuvenink, Rutger Jan Ploeg, Benedikt Mathias Kessler
Proteo-metabolomics reveals compensation between ischemic and non-injured contralateral kidneys after reperfusion. Scientific reports 8 (1) (2018)
Maria Kaisar, Leon F A van Dullemen, Marie-Laëtitia Thézénas, M Zeeshan Akhtar, Honglei Huang, Sandrine Rendel, Philip D Charles, Roman Fischer, Rutger J Ploeg, Benedikt Mathias Kessler
Plasma degradome affected by variable storage of human blood. Clinical proteomics 13 (2016)

Benedikt Mathias Kessler.css-eqlu8i{font-size:small;padding-left:4px;} (Benedikt Kessler, B M Kessler, Benedikt M Kessler)

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Benedikt Mathias Kessler (Benedikt Kessler, B M Kessler, Benedikt M Kessler)