Alexander Metz

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 12

Top Topics

Molecular Dynamics Simulations

Mycobacterium Tuberculosis

Top Venues

Acta crystallographica. Section D, Structural biology

This page only lists publications with an associated author ORCID identifier.

Publications

Subhadra Dalwani, Alexander Metz, Franziska U Huschmann, Manfred S Weiss, Rikkert K Wierenga, Rajaram Venkatesan
Crystallographic fragment-binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate-channeling path between them. Acta crystallographica. Section D, Structural biology (2024)
Subhadra Dalwani, Alexander Metz, Franziska U Huschmann, Manfred S Weiss, Rikkert K Wierenga, Rajaram Venkatesan
Crystallographic fragment-binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate-channeling path between them. Acta crystallographica. Section D, Structural biology 80 (Pt 8) (2024)
Chia Yiang Huang, Alexander Metz, Roland Lange, Nadia Artico, Céline Potot, Julien Hazemann, Manon Müller, Marina Dos Santos, Alain Chambovey, Daniel Ritz, Deniz Eris, Solange Meyer, Geoffroy Bourquin, May Sharpe, Aengus Mac Sweeney
Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket. Acta crystallographica. Section D, Structural biology 80 (Pt 2) (2024)
Chia Yiang Huang, Alexander Metz, Roland Lange, Nadia Artico, Céline Potot, Julien Hazemann, Manon Müller, Marina Dos Santos, Alain Chambovey, Daniel Ritz, Deniz Eris, Solange Meyer, Geoffroy Bourquin, May Sharpe, Aengus Mac Sweeney
Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket. Acta crystallographica. Section D, Structural biology (2024)
Subhadra Dalwani, Alexander Metz, Franziska U Huschmann, Manfred S Weiss, Rikkert K Wierenga, Rajaram Venkatesan
Crystallographic fragment-binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate-channeling path between them. Acta crystallographica. Section D, Structural biology 80 (Pt 8) (2024)
Chia Yiang Huang, Alexander Metz, Roland Lange, Nadia Artico, Céline Potot, Julien Hazemann, Manon Müller, Marina Dos Santos, Alain Chambovey, Daniel Ritz, Deniz Eris, Solange Meyer, Geoffroy Bourquin, May Sharpe, Aengus Mac Sweeney
Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket. Acta crystallographica. Section D, Structural biology 80 (Pt 2) (2024)
Subhadra Dalwani, Alexander Metz, Franziska U Huschmann, Manfred S Weiss, Rikkert K Wierenga, Rajaram Venkatesan
Crystallographic fragment-binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate-channeling path between them. Acta crystallographica. Section D, Structural biology 80 (Pt 8) (2024)
Chia Yiang Huang, Alexander Metz, Roland Lange, Nadia Artico, Céline Potot, Julien Hazemann, Manon Müller, Marina Dos Santos, Alain Chambovey, Daniel Ritz, Deniz Eris, Solange Meyer, Geoffroy Bourquin, May Sharpe, Aengus Mac Sweeney
Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket. Acta crystallographica. Section D, Structural biology 80 (Pt 2) (2024)
Chia Yiang Huang, Alexander Metz, Roland Lange, Nadia Artico, Céline Potot, Julien Hazemann, Manon Müller, Marina Dos Santos, Alain Chambovey, Daniel Ritz, Deniz Eris, Solange Meyer, Geoffroy Bourquin, May Sharpe, Aengus Mac Sweeney
Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket. Acta crystallographica. Section D, Structural biology 80 (Pt 2) (2024)
Karen Vester, Alexander Metz, Simon Huber, Bernhard Loll, Markus C Wahl
Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta crystallographica. Section D, Structural biology (2023)
Alexander Metz, Jan Wollenhaupt, Steffen Glöckner, Niki Messini, Simon Huber, Tatjana Barthel, Ahmed Merabet, Hans Dieter Gerber, Andreas Heine, Gerhard Klebe, Manfred S Weiss
Frag4Lead: growing crystallographic fragment hits by catalog using fragment-guided template docking. Acta crystallographica. Section D, Structural biology 77 (Pt 9) (2021)
Janis Müller, Romina A Kirschner, Jan-Philipp Berndt, Tobias Wulsdorf, Alexander Metz, Radim Hrdina, Peter Richard Schreiner, Armin Geyer, Gerhard Klebe
Diamondoid Amino Acid-Based Peptide Kinase A Inhibitor Analogues. ChemMedChem 14 (6) (2019)