Amy C H Lee (Amy C-H Lee)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 7

Top Topics

Hyaluronic Acid

Circulating Tumor

Hepatitis B Virus

Top Venues

Journal of medicinal chemistry

ACS infectious diseases

Hepatology communications

This page only lists publications with an associated author ORCID identifier.

Publications

Dimitar Gotchev, Bruce D Dorsey, Duyan Nguyen, Ramesh Kakarla, Benjamin Dugan, Shuai Chen, Min Gao, Laurèn Bailey, Fei Liu, Troy Harasym, Tim Chiu, Sunny Tang, Amy C H Lee, Andrew G Cole, Michael J Sofia
Structure-Activity Relationships and Discovery of ( S )-6-Isopropyl-2-methoxy-3-(3-methoxypropoxy)-10-oxo-5,10-dihydro-6 H -pyrido[1,2- h ][1,7]naphthyridine-9-carboxylic Acid (AB-452), a Novel Orally Available HBV RNA Destabilizer. Journal of medicinal chemistry 67 (2) (2024)
Dimitar Gotchev, Bruce D Dorsey, Duyan Nguyen, Ramesh Kakarla, Benjamin Dugan, Shuai Chen, Min Gao, Laurèn Bailey, Fei Liu, Troy Harasym, Tim Chiu, Sunny Tang, Amy C H Lee, Andrew G Cole, Michael J Sofia
Structure-Activity Relationships and Discovery of ( S )-6-Isopropyl-2-methoxy-3-(3-methoxypropoxy)-10-oxo-5,10-dihydro-6 H -pyrido[1,2- h ][1,7]naphthyridine-9-carboxylic Acid (AB-452), a Novel Orally Available HBV RNA Destabilizer. Journal of medicinal chemistry (2024)
Dimitar Gotchev, Bruce D Dorsey, Duyan Nguyen, Ramesh Kakarla, Benjamin Dugan, Shuai Chen, Min Gao, Laurèn Bailey, Fei Liu, Troy Harasym, Tim Chiu, Sunny Tang, Amy C H Lee, Andrew G Cole, Michael J Sofia
Structure-Activity Relationships and Discovery of ( S )-6-Isopropyl-2-methoxy-3-(3-methoxypropoxy)-10-oxo-5,10-dihydro-6 H -pyrido[1,2- h ][1,7]naphthyridine-9-carboxylic Acid (AB-452), a Novel Orally Available HBV RNA Destabilizer. Journal of medicinal chemistry 67 (2) (2024)
Andrew G Cole, Steven G Kultgen, Nagraj Mani, Kristi Yi Fan, Andrzej Ardzinski, Kim Stever, Bruce D Dorsey, Eugen F Mesaros, Emily P Thi, Ingrid E Graves, Sunny Tang, Troy O Harasym, Amy C H Lee, Andrea Olland, Robert K Suto, Michael J Sofia
Rational Design, Synthesis, and Structure-Activity Relationship of a Novel Isoquinolinone-Based Series of HBV Capsid Assembly Modulators Leading to the Identification of Clinical Candidate AB-836. Journal of medicinal chemistry (2024)
Man Fung Yuen, Elina Berliba, Wattana Sukeepaisarnjaroen, Sang Hoon Ahn, Tawesak Tanwandee, Young Suk Lim, Yun Joon Kim, Kittiyod Poovorawan, Pisit Tangkijvanich, Christian Schwabe, Timothy Eley, Joanne Brown, Amy C H Lee, Emily P Thi, Bhavna Paratala, Nagraj Mani, Michael J Sofia, Gaston Picchio, Karen D Sims, Edward J Gane
Safety, pharmacokinetics, and antiviral activity of the capsid inhibitor AB-506 from Phase 1 studies in healthy subjects and those with hepatitis B. Hepatology communications 6 (12) (2022)
Xin Ye, Chise Tateno, Emily P Thi, Masakazu Kakuni, Nicholas M Snead, Yuji Ishida, Trisha R Barnard, Michael J Sofia, Takashi Shimada, Amy C H Lee
Hepatitis B Virus Therapeutic Agent ARB-1740 Has Inhibitory Effect on Hepatitis Delta Virus in a New Dually-Infected Humanized Mouse Model. ACS infectious diseases 5 (5) (2018)
Emily P Thi, Ammen P Dhillon, Andrzej Ardzinski, Lale Bidirici-Ertekin, Kyle D Cobarrubias, Andrea Cuconati, Andrew S Kondratowicz, Kaylyn Kwak, Alice H L Li, Angela Miller, Chris Pasetka, Luying Pei, Janet R Phelps, Nicholas M Snead, Xiaohe Wang, Xin Ye, Michael J Sofia, Amy C H Lee
ARB-1740, a RNA Interference Therapeutic for Chronic Hepatitis B Infection. ACS infectious diseases 5 (5) (2018)